Canno Restore · 2% Nano-CBD
CANNO RESTORE CREAM (2% NANO-CBD)
Price: $68.00
Botanical InnovationWhere nature
Where nature
meets science.
Advanced botanical formulations for everyday wellness, developed through evidence-driven research and our proprietary delivery technology.
Research Driven
Evidence-informed development
Botanical Focus
Purposeful plant-derived ingredients
Advanced Delivery
Proprietary nano technology
Practice Ready
Built for professional partnerships
Nuvo Botanix advances everyday wellness through evidence-driven botanical formulation science and an uncompromising commitment to ingredient quality.
Every formula is built on rigorous research and a commitment to quality, delivering the potential of botanical actives at a level the body can actually use.
Shop Canno Restore™
Everyday recovery and comfort support.
Available in 2% and 3% Nano-CBD strengths, plus a 12-unit CANNO RESTORE+ case for healthcare-provider offices.
Canno Restore+ · 3% Nano-CBD
CANNO RESTORE+ CREAM (3% NANO-CBD)
Price: $88.00
Healthcare Provider Case · 12 Units
CANNO RESTORE+ CREAM (3% NANO-CBD) - HCP (12 units)
Price: $780.00
12 units · $65.00 per unit · Regular MSRP $88.00 per unit
Our Goal
Health by Nature: Advancing the science of botanical formulations.
We combine thousands of years of botanical knowledge with rigorous clinical methodology to create formulations that perform at a level neither traditional remedies nor synthetic alternatives could reach alone.
Proprietary Technology
Biotechnology formulation science that works with the skin's own biology.
Our proprietary lipid nanoparticle delivery system is designed to work with the skin's natural lipid matrix, helping botanical actives reach deeper layers where targeted delivery and performance matter most.
The result: formulations that actually penetrate the skin and perform at a level conventional topicals simply cannot reach.
How Cannano™ Technology worksCanno Restore™
Recovery support, designed for everyday use.
A closer look at Canno Restore Cream and the compact airless format designed for simple, measured application at home or on the go.
Physician Perspectives
What physicians are saying.
Statements from the physician scientist behind Cannano Technology and dermatologists who have worked with Canno Cream in clinical practice.
“As a Dermatologist, I have been recommending Canno Cream to my patients for several years as an adjunctive topical therapy for inflammatory skin conditions such as eczema and dermatitis. Many of my patients have reported noticeable improvements in lesion appearance, reduced erythema, and decreased irritation.”
Apple Bodemer, MD
Integrative Dermatologist & Clinical Associate Professor in the Department of Dermatology at the University of Wisconsin School of Medicine and Public Health
“Having evaluated Canno Cream clinically over several years, I have observed consistently positive patient experiences across a range of inflammatory skin concerns. The underlying science is particularly compelling: the formulation utilizes nano-scale CBD delivery designed to improve topical bioavailability and interaction with the skin’s endocannabinoid system, which is involved in regulating cutaneous inflammation, immune signaling, and barrier homeostasis. Based on my clinical experience, Canno Cream represents a promising science-driven approach to supporting patients with inflammatory and reactive skin.”
Daniel M. Siegel, MD, MS, FAAD, FACMS, CPCD
Clinical Professor of Dermatology, SUNY Downstate Health Sciences University, Past President, American Academy of Derm
Inventor of Cannano Technology
“Paving the way for the future of natural & safe cannabinoid therapeutics.”
Michael Milane, MD, MBA, MPH
Physician Scientist & Inventor of Cannano Technology
About Cannano™ TechnologyPhysician statements reflect the individual clinical experience and opinions of the physicians quoted. Individual results vary.
★★★★★ Customer Feedback
Real relief, in their own words
Feedback shared directly by Canno Restore™ customers.
★★★★★
“Strength training left me sore for 4–5 days despite proper nutrition and recovery. This has been uniquely effective in reducing muscle discomfort and soreness — compared to other CBD and lotion products. I will continue to use it.”
★★★★★
“Within a couple of days, I noticed a real difference. It's helped me work out more without the knee pain I was experiencing. I've also used it on bug bites — takes the itch away better than cortisone creams have for me.”
★★★★★
“There are no words to describe how this cream has made a difference in my daily life. But until you try it, you will not understand the standard of relief.”
★★★★★
“I want to express my sincere gratitude. Despite icing, castor oil, and arnica treatments, I couldn't get the swelling from a hand injury to go down — daily use brought greater comfort, improved mobility, and easier daily activities.”
Individual experiences vary. Customer testimonials describe personal experiences and are not a guarantee of results.
Our Perspective
“True wellness thrives where ancient botanical wisdom meets modern scientific precision: This is health by nature.”
Connect with Nuvo Botanix
Interested in learning more about Nuvo Botanix?
Connect with our team to learn more about Nuvo Botanix, our research-driven approach, and future partnership opportunities.